Incomplete Antibodies May Reduce ABO Cross-Match Incompatibility: A Pilot Study

Incomplete Antibodies May Reduce ABO Cross-Match Incompatibility: A Pilot Study

OBJECTIVE Any erythrocyte transfusion among humans having type A or B blood groups is impossible due to antibodies causing fatal transfusion complications. A cross-match test is performed to prevent immune transfusion complications before transfusion. Our hypothesis is that the fragment antibody (Fab) part of the antibody (incomplete antibody) may be used to prevent an immune stimulus related t...

ABO incompatibility: which one matters?

ABO Bloods group incompatibility in recurrent abortion

Abstract Background A vast variety of factors may cause recurrent pregnancy loss. Blood group incompatibility of parents could cause abortion. The examination of couples or twins, blood groups showed that the blood group incompatibility can affect adversely the outcome of pregnancy. Couples with blood group incompatibility are more involved in spontaneous miscarriage. Antigenes in two differe...

Hydrops fetalis due to ABO incompatibility.

Hemolytic disease of the newborn due to ABO incompatibility was first observed by Halbrecht in 1944. This entity has a spectrum ranging from minimal hemolysis requiring no therapy, as is the case in most instances, to severe hemolytic disease requiring aggressive management including exchange transfusion in a small percentage of cases. An extreme degree of hemolytic disease of the newborn due t...

Specific and cross-reacting antibodies in ABO heterospecific twin pregnancy.

Wit/i the assistance of KATHRYN BEAVFIE T HE SUB.JECT of this report is an unusual experiment of nature imivolving a pair of twins of different A and B blood groups bormi to a group 0 mother. The devebopmemit of frank hemolytic disease in the twin hebongimig to blood group B, in the absence of recognizable abmiormalities imi the group A twin was the indication for a detailed study of the behavi...